Trulicity dulaglutide

Trulicity (Dulaglutide)

Trulicity contains dulaglutide, a GLP-1 receptor agonist used to improve blood-glucose control in adults and children aged 10 years and above with type 2 diabetes. It is used alongside diet and exercise and is administered once weekly by subcutaneous injection.

Trulicity is a prescription-only medicine. Treatment should be prescribed and monitored by an appropriately qualified healthcare professional.

What is Trulicity?

Trulicity contains the active ingredient dulaglutide. It belongs to the GLP-1 receptor agonist class of medicines.

Dulaglutide works through GLP-1 receptors involved in blood-glucose regulation. It can help improve glycaemic control when used alongside appropriate dietary and lifestyle measures.

How Does Trulicity Work?

Dulaglutide mimics the activity of naturally occurring GLP-1. It helps stimulate insulin secretion when blood glucose levels are elevated and reduces glucagon secretion when appropriate. It also slows gastric emptying and may influence appetite.

Trulicity Dose Information

The appropriate Trulicity dose depends on the individual treatment plan and the prescribing information applicable to the patient.

For adults, treatment commonly begins with 0.75 mg once weekly. Depending on glycaemic response and tolerability, the dose may be increased according to the official prescribing information.

Do not change your Trulicity dose without medical advice.

How is Trulicity Administered?

Trulicity is administered once weekly as a subcutaneous injection. It can be injected into the abdomen, thigh or upper arm according to the instructions supplied with the medicine.

Your healthcare professional should explain how to use the device correctly before you administer Trulicity yourself.

Who May Use Trulicity?

Trulicity is used for the treatment of type 2 diabetes when blood-glucose control is insufficient despite appropriate diet and exercise. It may be used alone or alongside other diabetes medicines, depending on the patient’s circumstances.

Eligibility and treatment decisions should always be determined by a healthcare professional.

Important Safety Information

• Trulicity is a prescription-only medicine.
• Use Trulicity exactly as prescribed.
• Common adverse effects can include nausea, diarrhoea, vomiting, abdominal pain and other gastrointestinal symptoms.
• Tell your healthcare professional about all medicines you take, particularly insulin or sulfonylureas.
• Patients using medicines that can cause hypoglycaemia may require additional monitoring.
• Seek medical advice if you experience severe or persistent abdominal pain.
• Do not combine Trulicity with another GLP-1 receptor agonist unless specifically instructed by your healthcare professional.

Product Information

• Active ingredient: Dulaglutide
• Drug class: GLP-1 receptor agonist
• Administration: Subcutaneous injection
• Frequency: Once weekly
• Indication: Type 2 diabetes
• Legal category: Prescription-only medicine

Trulicity Compared With Other GLP-1 Medicines

Trulicity contains dulaglutide, while other medicines in this therapeutic area contain different active ingredients. For example, Ozempic and Rybelsus contain semaglutide, while Mounjaro contains tirzepatide.

These medicines have different authorised indications, dosing schedules and administration methods. They should not be substituted for one another without professional medical advice.

Related Products and Information

If you are researching prescription medicines for type 2 diabetes, visit our Diabetes Medicines category for related products.

For information about prescription weight-management treatments, explore our Weight Management category.

You can also read our health and medicine articles for additional educational information.

Official UK Medicine Information

For complete information about Trulicity, including contraindications, warnings, interactions, adverse effects and dosing, consult the official Trulicity Summary of Product Characteristics and Patient Information Leaflet.

Frequently Asked Questions

What is Trulicity?

Trulicity is a prescription medicine containing dulaglutide, a GLP-1 receptor agonist used to improve blood-glucose control in people with type 2 diabetes.

What is the active ingredient in Trulicity?

The active ingredient is dulaglutide.

How often is Trulicity taken?

Trulicity is administered once weekly by subcutaneous injection.

What is the starting dose of Trulicity?

The usual adult starting dose is 0.75 mg once weekly. Dose adjustments should be made according to the official prescribing information and advice from your healthcare professional.

Is Trulicity a weight-loss medicine?

Trulicity is authorised primarily for the treatment of type 2 diabetes. It should not be presented as a substitute for medicines specifically authorised for weight management.

Can Trulicity be taken with Ozempic?

Trulicity should not be combined with another GLP-1 receptor agonist unless specifically instructed by an appropriate healthcare professional.

Is Trulicity prescription only?

Yes. Trulicity is a prescription-only medicine in the UK.

Where can I find official Trulicity information?

The UK electronic Medicines Compendium provides the official Trulicity Summary of Product Characteristics and Patient Information Leaflet.